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Synephrine HCl

CAS No. 5985-28-4

Synephrine HCl ( Oxedrine hydrochloride )

产品货号. M18871 CAS No. 5985-28-4

SynephrineHCl (Oxedrine, p-Synephrine) 是一种作用于拟交感神经 α-肾上腺素能受体 (AR) 的激动剂。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ¥235 有现货

生物学信息

  • 产品名称
    Synephrine HCl
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SynephrineHCl (Oxedrine, p-Synephrine) 是一种作用于拟交感神经 α-肾上腺素能受体 (AR) 的激动剂。
  • 产品描述
    SynephrineHCl (Oxedrine, p-Synephrine) is an agonist that acts on sympathomimetic α-adrenergic receptor (AR).(In Vivo):Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine.
  • 体外实验
    ——
  • 体内实验
    Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine. Animal Model:Portal vein ligation (PVL) or bile duct ligation (BDL) rats Dosage:1 mg/kg per 12 hours Administration:Oral gavage; for 8 days Result:The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.
  • 同义词
    Oxedrine hydrochloride
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    α-adrenergic receptor
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    5985-28-4
  • 分子量
    203.67
  • 分子式
    C9H13NO2·HCl
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO : ≥ 52 mg/mL; 255.31 mM
  • SMILES
    C(c1ccc(cc1)O)(CNC)O.Cl
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Huang YT, et al. Jpn J Pharmacol, 2001, 85(2), 183-188.
产品手册
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